Publications - Bioimaging and Biophotonics Laboratory

^#equal contribution, *corresponding author

Changes in Outer Nuclear Layer Thickness After Treatment of Chronic XXX

H.S. Yang^#, T. Kim^#, T. Um^#, Y.-H. Jo, D. Koo, and J. Kim*

Submitted

Therapeutic Potential of XXX on Pterygium Cells

D. Koo^#, M. Kim^#, H.S. Yang^#, and J. Kim*

Submitted

UV curable resin as a rapid and superior sealant for STORM

Y. Lee^#, M. Lee^#, Y. Park^#, C. Kim, and J. Kim*

Biomedical Optics Express (in press)

UV curable resin provides rapid, air-tight sealing for STORM, extending MEA/GLOX buffer lifetime and enabling high-quality imaging for 48 h—outperforming conventional sealants such as nail polish, CytoSeal 60, and 5-min epoxy.

Yes-Associated Protein (YAP) Is Associated with Disease Severity and Visual Prognosis in Epiretinal Membrane

H.S. Yang^#, Y.-H. Jo^#, D. Kim, S. Choi, B.G. Moon, Y. Lee, M. Kim, D. Koo, and J. Kim*

Investigative Ophthalmology & Visual Science 66(11):39 (2025)

We identified Yes-Associated Protein (YAP) as a prognostic biomarker in epiretinal membrane.

Micro-fragmented Collagen Hydrogel Wound Dressing: Enhanced Porosity Facilitates Elevated Stem Cell Survival and Paracrine Effects for Accelerated Wound Maturation

C. Hong, Y. Lee, H. Chung, D. Kim, J. Kim, J.W. Kim, K. Lee*, S.-H. Kim*

Materials Today Bio 101678 (2025)

Hydrogel-encapsulated stem cells accelerate wound healing through enhanced survival and paracrine activity.

Epiretinal Membrane: Correlations among Clinical, Immunohistochemical, and Biochemical Features and their Prognostic Implications

H.S. Yang, S. Choi, S. Kim, C.H. Min, D. Kim, Y. Lee, M. Kim, D. Koo, J. Ryu, and J. Kim*

Investigative Ophthalmology & Visual Science 65(14):25 (2024)

Preoperative vision, OCT irregularity, myofibroblasts, and RPE cells predict postoperative visual outcomes in ERM.

A micro-fragmented collagen gel as a cell-assembling platform for critical limb ischemia repair

H. Chung, J.-K Choi, C. Hong, Y. Lee, K.H. Hong, S.J. Oh, J. Kim, S.-C. Song, J.-W. Kim, and S.-H Kim*

Bioactive Materials 34, 80-97 (2024)

“A simple, cost-effective, and cytocompatible approach for the fabrication of collagen microgel (CMG) as a novel scaffold to improve transplantation efficiency of stem cell therapy at injury site.”

Nonparaxial Imaging Theory for Differential Phase Contrast Imaging

Jeongmin Kim*

Current Optics and Photonics 7, 537-544 (2023)

A nonparaxial DPC imaging equation with a transmission cross-coefficient (TCC) has been derived to improve phase retrieval accuracy in high-NA quantitative phase imaging (QPI).

Line spectroscopic reflectometry for rapid and large-area thickness measurement

M. Lee^#, J. Park^#, and J. Kim*

Optics Express 31, 32241-32252 (2023)

We introduce line spectroscopic reflectometry (LSR), a technique that extends traditional point-based SR to line measurements, enabling rapid thickness measurement across large areas.

Enhancing obSTORM imaging performance with cubic spline PSF modeling

D. Koo^#, M. Lee^#, Y. Lee, and J. Kim*

Biomedical Optics Express 14, 5075-5084 (2023)

We enhanced oblique plane microscopy-based single molecule localization microscopy (obSTORM) with a cubic spline PSF model, improving 3D localization precision, imaging resolution, and axial range in volumetric imaging.

STORM Imaging Buffer with a Refractive Index Matched to Standard Immersion Oil

Y. Lee, Y. Lee, M. Lee, D. Koo, D. Kim, H. Kim, K. Lee, and J. Kim*

ACS Photonics 10, 2589-2597 (2023)

We have, for the first time, developed an oil-index-matching STORM buffer that enhances imaging depth, resolution, and stability in thick tissues by reducing light scattering through improved index matching.

Recent advances in oblique plane microscopy

Jeongmin Kim*

Nanophotonics 12, 2317-2334 (2023)

This invited review provides an overview of oblique plane microscopy (OPM), covering its unique high-speed volumetric imaging capabilities, recent advancements, and broad applications in biology, medicine, and materials science.

The Relationship Between Retinal and Choroidal Thickness and Adiponectin Concentrations in Patients with Type 2 Diabetes Mellitus

H.S. Yang, Y.J. Choi, H.Y. Han, H.S. Kim, S.Y. Park, J. Kim, and S. Choi*

Investigative Ophthalmology & Visual Science 64(4):6 (2023)

This study found that elevated adiponectin levels correlate with increased severity of diabetic retinopathy.

Simple and fast calibration method for phase-only spatial light modulators

M. Lee^#, D. Koo^#, and J. Kim*

Optics Letters 48, 5-8 (2022)

We introduce a fast and accurate calibration method using Twyman–Green interferometry to correct phase and optical flatness nonuniformities in liquid-crystal-on-silicon spatial light modulators (SLMs) at single-pixel resolution.

Subwavelength-scale lasing perovskite with ultrahigh Purcell enhancement

S. Yang^#, W. Bao^#, X. Liu^#, J. Kim, R. Zhao, R. Ma, Y. Wang, and X. Zhang*

Matter 4, 4042-4050 (2021)

This work demonstrates a ultrafast and stable perovskite laser with high Purcell enhancement, providing a promising platform for integrated photonics and optoelectronics.

A weak link with actin organizes tight junctions to control epithelial permeability

B. Belardi^#, T. Hamkins-Indik^#, A. R. Harris, J. Kim, K. Xu, and D. A. Fletcher*

Developmental Cell 54, 1-13 (2020)

This study identifies a key sequence in ZO-1 that regulates tight junction (TJ) permeability via weak actin binding, offering a potential target for treating transport disorders and improving drug delivery.

Publications before joining SNU

Room-temperature giant Stark effect of single photon emitter in van der Waals material

Y. Xia^#, Q. Li^#, J. Kim, W. Bao, C. Gong, S. Yang, Y. Wang, and X. Zhang*

Nano Letters 19, 7100-7105 (2019)

Observation of Rydberg exciton polaritons and their condensate in a perovskite cavity

W. Bao^#, X. Liu^#, F. Xue^#, F. Zheng, R. Tao, S. Wang, Y. Xia, M. Zhao, J. Kim, S. Yang, Q. Li, Y. Wang, Y. Wang, L.-W. Wang, A.H. MacDonald*, and X. Zhang*

Proceedings of the National Academy of Sciences, USA 116, 20274-20279 (2019)

Oblique-plane single-molecule localization microscopy for tissues and small intact animals

J. Kim, M. Wojcik, Y. Wang, S. Moon, E.A. Zin, N. Marnani, Z.L. Newman, J.G. Flannery, K. Xu*, and X. Zhang*

Nature Methods 16, 853-857 (2019)